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Participant
organisation name

Principal
investigator

Researchers

Coordinator
of work
package

Focus
of national
study

Radboud University
Nijmegen Medical Centre

M. Wensing

J. van Lieshout,
R. Klomp

3,6

Cardiovascular risk management

Department of Health
Sciences, University
of Leicester,
United Kingdom

R. Baker

P. Sinfield,
J. Kraus

2

Obesity

University Newcastle
upon Tyne,
United Kingdom

M. Eccles

C. Wiscombe,
A. Blindova

   

Norwegian Knowledge Centre
for the Health Services,
Norway

A.D. Oxman

S. Flottorp,
E. Aakhus,
J. Odgaard-Jensen

1

Depression in elderly

University Hospital
Heidelberg, Germany

J. Szecsenyi

C. Jäger,

J. Steinhäuser

 

4

Multimorbidity

Ottawa Hospital
Research Institute,
Canada

J. Grimshaw

V. Lybanon
Daigle

   

Medical University
of Lodz, Poland

M. Godycki-Cwirko

A. Kowalczyk,
J. Krawczyk
I. Zakowska

5

COPD

 

Partner 1 – Radboud University Nijmegen Medical Centre, The Netherlands (RUNMC)

Description of legal entity.
Radboud University Nijmegen Medical Centre is one of seven University Hospitals in The Netherlands. The Scientific Institute for Quality of Healthcare (IQ Healthcare) is a department at RUNMC, founded by Prof. Richard Grol in 1989 (www.iqhealthcare.nl). The department has a large research program and a growing volume of education in the field of quality and safety of healthcare. The research of IQ Healthcare is highly prominent in the Nijmegen Centre for Evidence Based Practice (www.ncebp.nl), which is one of the 20 research institutes of the Radboud University Nijmegen.

Main tasks in TICD.
RUNMC is responsible for project coordination (work package 6) and it coordinates research work package 3. It participates in the research work packages 2, 3 and 4, focusing on patients with high cardiovascular risk.

Previous experience.
The mission of IQ healthcare is to provide research evidence that supports decision makers in the field of quality and safety of healthcare. IQ healthcare is an internationally recognized centre for excellence with a broad research program, covering primary care, hospital care, nursing care, allied health professions, and medical ethics. Particularly strong and internationally recognized is the program of implementation science. The program includes a range of studies into cardiovascular primary care, including an international comparative study on cardiovascular risk management in 10 countries (EPA Cardio) and national research on cardiovascular risk. In 2009, the international EPA projects (led by IQ healthcare) were awarded with the European Health Forum Gastein Award. IQ healthcare is connected to many organizations, including the Dutch Ministery of Health, ZonMW (Dutch national funder of health research), specific health insurers, other universities and institutes, various organizations of health professionals, and a number of hospitals.

Profile of staff members.
Michel Wensing, Ph.D., medical care researcher and professor at RUNMC, is (co‐)author of >200 scientific publications and (co‐)supervisor of 20 Ph.D. theses and 17 M.Sc. theses. He has M.Sc. in sociology, Ph.D in medical sciences, and Habilitation in medical care research. He is associate editor of the journal Implementation Science since 2006, member of Scientific Advisory Committee of KT Canada and participant in the German nationwide program for development of performance indicators in healthcare. Since 1996 he has been involved in 3 European projects as principal researcher and in 3 other European projects as work package coordinator. He is also senior researcher at Heidelberg University Hospital (since 2002) and is visiting professor at Leicester University (since 2009).
Jan van Lieshout, MD Ph.d., is an experienced primary care physician and researcher at IQ healthcare with a research program focused on chronic illness care, focusing on cardiovascular conditions. He has been member of various guideline development groups for different cardiovascular diseases, wa member of the core group that coordinated an international observational study on cardiovascular risk management in primary care in 10 countries.
Rien Klomp, MD, M.Sc, is an experienced primary care physician and newly started researcher at IQ healthcare. He is responsible for the TICD research on cardiovascular primary care in the Netherlands.

Key publications
• Wensing M, Bosch M, Grol R. The Knowledge to Action Cycle: Developing and selecting knowledge to action interventions. CMAJ 2010; 182(2): E85-E88.
• Van Lieshout J, Wensing M, Campbell S, Grol R. Primary care strength linked to prevention programs for cardiovascular disease. Am J Manag Care 2009; 15:255‐262.
• Campbell S, Ludt S, Van Lieshout J, Boffin N, Wensing M, Petek D, Grol R, Roland M. Quality indicators for the prevention and management of cardiovascular disease in primary care in nine European countries. Eur J Cardiovasc Prev Rehab 2008;15:509‐515

Partner 2 – Department of Health Sciences,University of Leicester, United Kingdom

Description of legal entity.

The University is a research intensive university located in the East Midlands city of Leicester. Consistently ranked in the top 20 among UK universities, it ranked in the top 5% of universities worldwide and was the Times Higher University of the year in 2008‐9. Levels of student satisfaction are regularly at the top of the national league table, and research citation levels are 6th highest for size in the UK (THE/QS world ranking, 2009).The medical school at Leicester is based in the College of Medicine, Biological Sciences and Psychology. Research covers the broad spectrum of biomedical science with exceptional strength in Cancer Studies, Cardiovascular Sciences, Infection and Immunity, Health and Social Sciences, Genetics, Cell Physiology, Molecular and Structural Biology, Neuroscience and interactions with the MRC Toxicology Unit.

Main tasks in TICD.

University of Leicester leads research work package 2 and it participates in the research work packages 2, 3 and 4, focusing on obesity.

Previous experience.

The Department of Health Sciences is one of five departments in the medical school at Leicester, and has around 140 members of staff, including clinical academics, statisticians, social scientists psychologists and epidemiologists. Submitted to the epidemiology and public health panel at the 2008 RAE, the department achieved a grade point average of 2.65 (see: http://www.rae.ac.uk/results/quality). Researchers at the Department of Health Sciences have undertaken research of implementation methods for more than a decade. This work has included randomized controlled trials, systematic reviews, and qualitative and observational studies, and has culminated in the creation of a Collaboration for Leadership in Applied Health Research and Care (CLAHRC), funded £10m by England’s National Institute for Health Research (NIHR) plus a further £10m from local NHS partners and the University. The CLAHRC’s applied research programme addresses the major chronic conditions as well as the implementation of evidence to improve outcomes (see: http://www.lnr‐clahrc.org/). The Department of Health Sciences has the capacities to perform research in a range clinical domains, including obesity.

Profile of staff members.

Richard Baker, MD, is professor and director of the CLAHRC, and lead of its implementation theme, Head of the Department of Health Sciences, and a general practitioner. He is author of 170 peer reviewed publications, has been a collaborator in several EU‐funded projects, and was awarded NIHR Senior Investigator status in 2008. Research interests have included methods of translating evidence into practice, patient experience of care, and patient safety in primary care.

Paul Sinfield is the Theme Manager of the CLAHRC Implementation Theme, having joined the Department of Health Sciences in 2000. He has led research on a range of studies that have been primarily concerned with using patients’ and carers’ experiences of care to shape the delivery of services. He is author of 17 peer reviewed publications and has presented research findings at a number of conferences.

Key publications

Enriquez‐Puga A, Baker R, Paul S, Villoro‐Valdes R. Effect of outreach visit on general practice prescribing of antibiotics and antidepressants: a two‐year randomized controlled trial. Scan J Prim Care 2009; 27: 195‐201.

Baker R, Robertson N, Rogers R, Davies M, Brunskill N, Khunti K, Steiner M, Williams M, Sinfield P. The National Institute of Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLAHRC) for Leicestershire, Northamptonshire and Rutland (LNR): a programme protocol. Implementation Science 2009;4:72

Stokes T, Tarrant C, Mainous AG, Schers H, Freeman G, Baker R. Continuity of care: Is the personal doctor still relevant? A survey among general practitioners or family physicians in England and Wales, The United States and The Netherlands. Ann Fam Med 2005;3:353‐359.

 

Partner 3 – University Newcastle upon Tyne, United Kingdom (UNEW)

Description of legal entity.
Newcastle University is among the top 20 higher education institutions in the UK and is a member of the Russell Group, comprising 20 leadingresearch institutions in the UK. Within Newcastle University the Institute of Health and Society aims to transformhealth through the conduct of internationally recognised research on population health, health services andhealth‐related social science. The creation of the Institute of Health and Society in August 2006 builds on a strongfoundation of interdisciplinary health services, public health and social science research conducted both in the UKand several overseas countries. The Effective Practice and Organisation of Care (EPOC) research programme (directed by Eccles) aims to improve patient outcomes through thereceipt of appropriate healthcare. It does through this by research of relevance to both healthcare professionalsand policy makers and includes the study of influences on healthcare professional and organisational behaviour. It is based within the DMOC (Decision Making and Organisation of Care) programme within IHS.

Profile of staff members.
Martin Eccles(MD) is professor and leads the Effective Practice and Organisation of Care Programme. He has attracted over £9 million in peer reviewed research income from a wide range of fundersincluding the UK Medical Research Council, Welcome Trust, UK NIHR R&D Programme and the European Union.He has published over 150 papers in peer reviewed journals, edited three books and written 34 book chapters. Heis an NIHR Senior Investigator, a Fellow of the Academy of Medical Sciences, the Royal College of Physicians, theRoyal College of General Practitioners and the Faculty of Public Health. He is a Visiting Professor at the OttawaHealth Research Institute, is founding Co‐Editor‐in Chief of the open access electronic journal ImplementationScience. He is currently running projects: examining theoretical determinants of quality of care in patients withdiabetes; deriving quality of care review criteria for UK primary care; conducting Cochrane EPOC reviews.

Main tasks in TICD.
University of Newcastle upon Tyne is involved in work package 1 (for updating the review oftailored interventions) and provides important intellectual input into the research work packages 2, 3 and 4. Dr.Eccles is currently one of the leading implementation researchers in the world and his active involvement in thevarious work packages will be bring the TICD project to a higher level.

Key publications
• Francis JJ; Stockton C; Eccles MP; Johnston M; Cuthbertson BH; Grimshaw JM; Hyde C; Tinmouth A; Stanworth SJ. Evidence-based selection of theories for designing behaviour change interventions: Using methods based on theoretical construct domains to understand clinicians' blood transfusion behaviour. British Journal of Health Psychology 2009,14 625-646.
• Bonetti D, Johnston M, Clarkson JE, Grimshaw J, Pitts NB, Eccles M, Steen N, Thomas R, Maclennan G, Glidewell L, Walker A. Applying psychological theories to evidence-based clinical practice: identifying factors predictive of placing preventive fissure sealants. Implementation Science 2010, 5:25.
• Gardner, B., Whittington, C., McAteer, J., Eccles, M., Michie, S. Using theory to synthesise evidence from behaviour change interventions: The example of audit and feedback. Social Science & Medicine 2010, 70 (10), 1618-1625.
• Ramsay CR, Thomas RE, Croal BL, Grimshaw JM, Eccles MP. Using the theory of planned behaviour as a process evaluation tool in randomised trials of knowledge translation strategies: A case study from UK primary care. Implementation Science 2010, 5:71. doi:10.1186/1748-5908-5-71.
• Little EA, Eccles MP. A systematic review of the effectiveness of interventions to improve post-fracture investigation and management of patients at risk of osteoporosis. Implementation Science 2010; 5: 80.
• Francis JJ, Johnston M, Robertson C, Glidewell L, Entwistle V, Eccles MP, Grimshaw JM. What is an adequate sample size? Operationalising data saturation for theory-based interview studies. Psychology & Health 2010; 25(10): 1229-1245.
• Parmelli E, Flodgren G, Beyer F, Baillie N, Schaafsma ME, Eccles MP. The effectiveness of strategies to change organisational culture to improve healthcare performance: a systematic review. Implementation Science 2011, 6:33. Highly Accessed.
• Grimshaw JM, Eccles MP, Steen N, Johnston M, Pitts NB, Glidewell E, Maclennan G, Thomas R, Bonetti D, Walker A. Applying psychological theories to evidence-based clinical practice: Identifying factors predictive of lumbar spine x-ray for low back pain in UK primary care practice. Implementation Science 2011,6:55.
• Eccles MP, Hrisos S, Francis JJ, Stamp E, Johnston M, Hawthorne G, Steen N, Grimshaw JM, Elovainio M, Presseau J, Hunter M. Instrument development, data collection and characteristics of practices, staff and measures in the Improving Quality of Care in Diabetes (iQuaD) Study. Implementation Science 2011, 6:61, doi:10.1186/1748-5908-6-61.
• Hrisos S, Eccles MP, Francis JJ, Bosch M, Dijkstra R, Johnston M, Grol R. Kaner EF, Steen IN. Using psychological theory to understand the clinical management of type 2 diabetes in primary care: a comparisonacross two European countries. BMC Health Serv Res 2009;9:140.
• Goh TT, Eccles MP, Steen N. Factors predicting team climate, and its relation with quality of primary care.BMC Health Serv Res 2009;9:138.
• Grimshaw J, Eccles M, Thomas R, MacLennan G, Ramsay C, Fraser C, Vale L. Toward evidence‐based qualityimprovement. Evidence (and its limitations) of the effectiveness of guideline dissemination andimplementation strategies 1966‐1998. J Gen Intern Med 2006;21:S14‐20.

 

Partner 4 – Norwegian Knowledge Centre for the Health Services, Norway (KS)

Description of legal entity.
The Norwegian Knowledge Centre for the Health Services was founded in 2004. The Centre is organised under The Directorate for Health, but is scientifically and professionally independent. Its mission is to gather and disseminate evidence about the effects of interventions within all parts of the health services. The uptake of this evidence by the health services is an important goal for the Centre’s activities. A central task of the Centre is to support the government, the regional health authorities, and the health services in general to incorporate evidence into their practice. The Centre is based upon a merger of three organisations. One of these organisations, which is now part of the Department for evidence-based health services, has worked actively in the area of guideline development and implementation for two decades.

Main tasks in TICD.
The Centre will lead work package 1 (systematic reviews) and participate in the research work packages 2, 3 and 4, focusing on mental health.

Previous experience.
The research team has coordinated three previous Framework projects and is currently coordinating a fourth project: ReBEQI (Research Based Education and Quality Improvement, QLG4‐CT‐2002‐00657), Practihc (Pragmatic Randomized Controlled Trials in Healthcare, ICA4‐CT‐2001‐10019), SUPPORT (The SUPPORT Collaboration: Supporting Policy Relevant Reviews and Trials, PL‐031939), and SURE (Supporting the use of research evidence for policy in African health systems, GA‐222881). It has participated in four others: Changing Professional Practice (Biomed II), Eur‐Assess (Biomed II), and Afro‐Implement I and II (EC INCO). It has undertaken implementation research in Norway, including large cluster randomised trials of tailored interventions in primary care, an interrupted time series analysis of the impact of a national prescribing policy, surveys of healthcare professionals, and development of a consensus on continuing education and quality improvement in Norway. The focus of the research team is on developing and evaluating methods of helping patients, healthcare professionals and policy makers to make informed choices about healthcare. In addition to implementation research, it has undertaken research on translating research evidence into patient information, consumer involvement in healthcare, and the use of research evidence in health policymaking. The Centre hosts a satellite of the Cochrane Effective Practice and Organisation of Care Group and the Norwegian branch of the Nordic Cochrane Centre.

Profile of staff members.
Andy Oxman (MD, MSc) is a senior researcher who contributed to the development of evidence‐based medicine since he was at McMaster University from 1984‐94. He has been chair of the Cochrane Collaboration Steering Group and was the founding editor of its Handbook. He is a founding member and coordinator of the GRADE Working Group. He was a member of the WHO Advisory Committee on Health Research and chair of the Subcommittee on the Use of Research Evidence
Signe Flottorp (MD, PhD) is professor and head of the Board of the research programme on Health and care services research in The Research Council of Norway. She is still practicing part‐time as a GP and knows the challenges of bridging the gap between research evidence and practice both from the research and the clinical perspective.
Jan Odgaard‐Jensen (MSc) is a statistician and senior advisor for two Cochrane Review Groups. He has worked as a statistician on a number of systematic reviews, clinical phase III trials and effect studies.
Eivind Aakhus (MD) is a senior consultant in geriatric psychiatry, and has 20 years of clinical experience in psychiatry, of which ten years have been in the field of geriatric psychiatry. He has previously conducted small scientific projects.

Key publications
• Treweek S, Flottorp, Oxman AD. Improving the quality of primary care through tailored interventions and customisable software linked to electronic medical records. Health Informatics Journal 2000; 6:212-8.
• Oxman AD, Flottorp S. An overview of strategies to promote implementation of evidence based health care. In Silagy C, Haines A (eds.). Evidence Based Practice. 2nd Edition. London: BMJ Publishers, 2001, 101-19.
• Flottorp S, Oxman AD, Håvelsrud K, Treweek S, Herrin J. A cluster randomised trial of tailored interventions to improve the management of urinary tract infections and sore throat. BMJ 2002; 325:367-370.
• Scheel IB, Hagen KB, Herrin J, Oxman AD. A call for action: a randomized controlled trial of two strategies to implement active sick leave for patients with low back pain. Spine 2002; 27:561-6.
•Flottorp S, Oxman AD. Tailoring interventions to improve the management of urinary tract infections and sore throat: a pragmatic study using qualitative methods. BMC Health Services Research 2003; 3:3.
•Fretheim A, Oxman AD, Treweek S, Bjørndal A. Rational Prescribing in Primary Care (RaPP-trial). A randomised trial of a tailored intervention to improve prescribing of antihypertensive and cholesterol-lowering drugs in general practice. BMC Health Services Research 2003; 3:5.
•Fretheim A, Oxman AD, Flottorp S. Improving prescribing of antihypertensive and cholesterol-lowering drugs: a method for identifying and addressing barriers to change, BMC Health Services Research 2004, 4:23.
•Akl EA, Treweek S, Foy R, Francis J, Oxman AD. NorthStar, a support tool for the design and evaluation of quality improvement interventions in healthcare. Implementation Science 2007, 2:19 doi:10.1186/1748-5908-2-19
•Baker R, Camosso-Stefinovic J, Gillies C, Shaw EJ, Cheater F, Flottorp S, Robertson N. Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes. Cochrane Database of Systematic Reviews 2010, Issue 3. Art. No.: CD005470. DOI: 10.1002/14651858.CD005470.pub2.
•Aakhus E, Flottorp S, Oxman AD. Implementing evidence based guidelines for managing depression in elderly patients: A Norwegian perspective. Epidemiology and Psychiatric Sciences. In press 2012.
•Aakhus E, Flottorp S, Vandvik PO, Brandt L, Oxman A. Guidelines for the management of depression in primary health care, and their relevance for the depressed elderly: A systematic review. Protocol. http:// www crd york ac uk/PROSPERO/full_doc asp?ID=CRD42011001582 2011
•Engedal K, Kvaal K, Korsnes M, Barca ML, Borza T, Selbaek G, Aakhus, E. The validity of the Montgomery and Aasberg depression rating scale as a screening tool for depression in later life. Journal of Affective Disorders 2012; doi: 10.1016/j.jad.2012.02.042
•Aakhus E, Engedal K, Aspelund T, Selbaek G. Single session educational programme for caregivers of psychogeriatric in-patients--results from a randomised controlled pilot study. International Journal of Geriatric Psychiatry. 2009; 24:269-74


Partner 5 – University Hospital Heidelberg, Germany

Description of legal entity.

The Heidelberg University Hospital is one of the largest and most prestigious medical centers in Germany. The University is surrounded by internationally recognized research institutions, such as the German Cancer Research Center and the Max‐Planck‐Institute for Medical Research. The Department of General Practice and Health Services Research is one of the largest research centers in primary care and health services research in Germany with a staff of >45 employees, including 18 full time equivalent research staff based on external funding. The centre is leading a collaboration of all 5 medical faculties in Baden‐Württemberg, substantially funded by the Ministry of Science, Education and Arts, and aimed at improving primary care research and education. From 2004‐2010 the department has a large research grant from the Federal Ministry of Research and Education (BMBF) to improve research capacity in primary care. The department has an intensive collaboration with the AQUA‐institute on the topic of quality improvement.

Main tasks in TICD.

The department leads work package 4 and participates in the research work packages 2, 3 and 4, focusing on multi‐morbidity in elderly patients.

Previous experience.

The department has substantial experience in running large scale cluster randomized trials with up to 400 practices. The focus of these projects is to improve the care of chronically ill patients with disease entities such as diabetes, arthrosis, chronic heart failure by means of multifaceted interventions aiming at GPs, nurses and patients. Since 2008 it is collaborating in a large epidemiological study on multimorbidity. Other areas of research are complementary medicine, palliative care, evaluation of disease management programs and diagnostic studies. Additionally there is a morbidity and reason‐for‐encounter network based at the department which comprises longitudinal data of more than 100.000 individuals. The department has extensive experience with qualitative methods such as focus groups and interviews. In the international EPA cardio project the department supported participants from countries with a weak infrastructure in data acquisition and management. In the last years the department has participated in different EU‐wide research activities and coordinated large research projects on the German Disease Management Program for diabetes and on general practice centered care, a voluntary gate‐keeper model introduced in the German health care system since 2006.

Profile of staff members.

Joachim Szecsenyi (MD, MSc) is professor and head of the department since 2001, and holds academic degrees in social sciences and medicine. He has (co‐)authored >140 scientific publications and supervised more than 25 MD and PhD theses. In 1994 he was co‐founder and since then director of the AQUAInstitute for Applied Quality Improvement and Research in Health Care, which won in 2009 a bid for nationwide development and use of quality indicators in German hospital and ambulatory care. This large project comprises a multidisciplinary team of more than 40 researchers, IT‐specialists and supporting staff. It is funded by the Federal Joint Committee, a nationwide regulatory body in the statutory health care system. From 2002‐2008 he was president of the European Association for Quality in General Practice (EQuiP) a network association of the European Society of General Practice.

Key publications:

Szecsenyi J, Rosemann T, Joos S, Peters‐Klimm F, Miksch A. German diabetes disease management programs are appropriate to restructure care according to the Chronic Care Model – An evaluation with the Patient Assessment of Chronic Illness Care (PACIC‐5A) instrument. Diabetes Care 2008; 31: 1150‐1154

Peters‐Klimm F, Campbell S, Muller‐Tasch T, Schellberg D, Gelbrich G, Herzog W, Szecsenyi J. Primary carebased multifaceted, interdisciplinary medical educational intervention for patients with systolic heart failure: lessons learned from a cluster randomised controlled trial. Trials 2009; 10: 68.

Ose D, Wensing M, Szecsenyi J, et al. Impact of primary care‐based disease management on the healthrelated quality of life in patients with type 2 diabetes and co‐morbidity. Diabetes Care 2009; 32: 1‐7.

 

Partner 6 – Ottawa Hospital Research Institute, Canada

Description of legal entity.

The Ottawa Hospital (TOH) is the largest academic health sciences hospital in Canada. The Ottawa Hospital Research Institute (OHRI) is the research arm of TOH and is affiliated with the University of Ottawa. The Clinical Epidemiology Program is the main clinical and applied health research program within TOH focusing on practice and policy changing research to improve healthcare and patient outcomes. It includes 40 scientists from diverse backgrounds include medicine, nursing, epidemiology, health services research, statistics and psychology. It has five thematic areas of research: circulatory and respiratory health, emergency and critical care, maternal and fetal care, health services research (including knowledge translation) and methodological research.

Main tasks in TICD.

Ottawa Hospital Research Institute will provide important intellectual input into the research work packages 1 to 4, and contribute to linkage to KT Canada to enhance dissemination in work package 5. The linkage to the knowledge transfer community in Canada will bring the TICD at an internationally competitive level, because Canada is currently the leading country in implementation research in healthcare

Previous experience.

The KT research of the Clinical Epidemiology Program is done in three broad areas: first, systematic reviews of knowledge translation interventions (for example, dr. Grimshaw led a systematic review of guideline dissemination and implementation strategies that has been cited 350 times and downloaded over 110,000 times since it was published in 2004); secondly, large scale rigorous evaluations (mainly cluster randomized trials) of knowledge translation interventions, it has undertaken over 30 cluster randomized trials and several interrupted time series; thirdly advancing the methods and theory of knowledge translation, for example, it has undertaken a series of studies exploring the predictive value of psychological theories to explain variations in health professional behavior.

Profile of staff members.

Jeremy Grimshaw (MBChB, PhD) is an acknowledged international leader in knowledge translation and implementation research. He is a Senior Scientist in the Clinical Epidemiology Program, a full professor in the Department of Medicine at the University of Ottawa and holds a Tier 1 Canada Research Chair in Health Knowledge Transfer and Uptake. He is the Director of the Canadian Cochrane Centre and Network and Coordinating editor of the Cochrane Effective Practice and Organisation of Care review group. Prior to his current position, he was a Program Director in the Health Services Research Unit in Aberdeen, UK. He has over 280 peer reviewed publications in this area. He is the Principal Investigator of KT Canada (a team grant of approximately CAD 9.8 million from the Canadian Institutes of Health Research), the first national knowledge translation researcher involving six centres across Canada. He has previously collaborated with Partners 1, 3 and 4 in several EU funded projects (Changing Professional Practice, Afroimplement, REBEQI).

Key publications

Michie S, Fixsen D, Grimshaw JM, Eccles MP (2009). Specifying and reporting complex behaviour change interventions: the need for a scientific method. Implementation Science, 4:40.

Godin G, Bélanger‐Gravel A, Eccles M, Grimshaw J. Healthcare professionals' intentions and behaviors: A systematic review of studies based on social cognitive theories. Implementation Science 2008, 3:36

Grimshaw J, Zwarenstein M, Tetroe J, Godin G, Graham I, Lemyre L, Eccles M, Johnston M, Francis J, Hux J, O’Rourke K, Legare F, Presseau J (2007). Looking Inside the Black Box: A Theory Based Process Evaluation Alongside A Randomised Controlled Trial Of Printed Educational Materials (The Ontario Printed Educational Message (OPEM)) Trial [Registration number ISRCTN72772651]. Study Protocol Implementation Science, 2007 2:38.

Eccles M, Grimshaw J, Walker A, Johnston M, Pitts N, (2005). Changing the behaviour of healthcare

professionals: the use of theory in promoting the uptake of research findings. J Clin Epidemiol, 58(2), 107‐112.



Partner 7 –Medical University of Lodz, Poland

Description of legal entity.

The Medical University of Lodz (www.umed,lodz,pl) is the biggest state medical university in Poland, self‐depended in matters of science, teaching and management. The teaching, research and clinical structure of the University comprises the 9 faculties: two of Medicine; Dental Medicine; Pharmacy; Health Sciences; Physiotherapy; Nursing and Midwifery; Biomedical Sciences and Postgraduate Training; Military Faculty of Medicine; with 7 teaching hospitals and 77 departments. The University employs almost 1300 research and didactic staff, including 152 full professors, 133 assistant and associate professors as well as nearly 800 PhD academics; have almost 6000 students, over 300 postgraduate students and over 120 foreign students. Department of Family and Community Medicine develops activities in research, vocational training, postgraduate teaching, teaching the teachers. Research interests are respiratory tract (infections, asthma, COPD), postgraduate teaching, public health and prevention.

Main tasks.

MUL leads work package 5 on dissemination and participates in the research work packages 2, 3 and 4, focusing on asthma/COPD.

Previous experience.

The Department coordinated projects exploring physicians and patients perception of prevention; attitude towards diet counseling, physical exercise advice; prevention of CVD and COPD; attitude towards antibiotic use and resistance; respiratory and urinary tract infections; brief intervention in problem drinking, patients satisfaction and safety. Research on asthma and COPD is among the priorities of the department. At the moment the Department is a partner in EU 6th FP Network of Excellence GRACE; partner in within EU 6th FP project CHAMP; and EU 7th FP projects LINNEAUS‐EURO PC and SATURN. The Department coordinates the Network about 50 GPs participating in research and vocational training in family medicine. Researchers at the Department have experience in controlled trials, qualitative and observational studies.

Profile of staff members.

Maciek GodyckiCwirko (MD, PhD) family physician and public health specialist, is head of the Department of Family and Community Medicine. His research has focused on public health, particularly disease prevention and health promotion, health care systems, prudent use of medicines and patient safety in primary care. He is author of more than 30 peer‐reviewed publications and chapters in 20 textbooks. He has been member of various guideline development groups. As central researcher and coordinator has participated in numerous international projects, networks and committees. He is the president of the College of Family Physicians in Poland. He is also an auditor in EU Project ESAC. He will co‐ordinate work package 5 and supervise the research work in the work packages 2, 3 and 4.

Anna Kowalczyk (MPH) specialist in public health, research manager.

Key publications

Brotons C, Björkelund C, Bulc M, Godycki‐Cwirko M at al., Prevention and health promotion in clinical practice: the views of general practitioners in Europe, Preventive Medicine, 2004;40:595‐601.

Godycki‐Cwirko M, Koziarska‐Rosciszewska M, Kosiek K. The delivery of prevention programmes for cardiovascular disease and chronic obstructive pulmonary disease in Lodz by primary care physicians. Archives of Medical Science 2009 (in print).

Butler CC, Hood K, Verheij T, Little P, Melbye H, Nuttall J, Kelly M, Mölstad S, Godycki‐Cwirko M, et al. Acute cough in primary care: 13‐country prospective study of impact of variation in clinical presentation on antibiotic prescribing and recovery BMJ 2009;338:b2242

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